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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
32.12
Human Site:
Y606
Identified Species:
58.89
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
Y606
N
H
T
A
A
D
M
Y
L
S
P
V
R
S
P
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
Y753
N
H
T
A
A
D
M
Y
L
S
P
V
R
S
P
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
Y606
N
H
T
A
A
D
M
Y
L
S
P
V
R
S
P
Dog
Lupus familis
XP_534118
897
103170
Y575
N
H
T
A
A
D
M
Y
L
S
P
V
R
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
Y599
N
H
T
A
A
D
M
Y
L
S
P
L
R
S
P
Rat
Rattus norvegicus
P33568
920
105007
Y598
N
H
T
A
A
D
M
Y
L
S
P
I
R
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
Y595
S
H
T
A
A
D
L
Y
L
S
P
V
R
S
P
Chicken
Gallus gallus
Q90600
921
104417
Y598
N
H
T
A
A
D
L
Y
L
S
P
V
R
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
A585
G
E
Q
A
E
P
P
A
T
L
N
Q
P
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
R676
L
T
I
D
S
N
S
R
I
L
F
L
P
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
G456
E
V
V
M
V
T
F
G
Y
T
A
S
P
I
N
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
V715
R
N
S
F
T
S
P
V
K
D
R
L
L
G
N
Maize
Zea mays
Q3LXA7
1010
111475
S688
R
R
N
V
L
V
D
S
N
S
L
R
S
P
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
93.3
N.A.
6.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
N.A.
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
70
62
0
0
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
62
8
0
0
8
0
0
0
0
0
% D
% Glu:
8
8
0
0
8
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% G
% His:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
8
0
16
0
62
16
8
24
8
8
0
% L
% Met:
0
0
0
8
0
0
47
0
0
0
0
0
0
0
0
% M
% Asn:
54
8
8
0
0
8
0
0
8
0
8
0
0
0
16
% N
% Pro:
0
0
0
0
0
8
16
0
0
0
62
0
24
8
62
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
8
% Q
% Arg:
16
8
0
0
0
0
0
8
0
0
8
8
62
0
0
% R
% Ser:
8
0
8
0
8
8
8
8
0
70
0
8
8
62
0
% S
% Thr:
0
8
62
0
8
8
0
0
8
8
0
0
0
0
0
% T
% Val:
0
8
8
8
8
8
0
8
0
0
0
47
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _